Antiage: Where is the deciding game for healthy longevity? In the gut, where the anti-aging high command is driven by a super-bio triumvirate: the microbiota, the gut itself and the visceral brain, which interact closely with each other. First thought: the human genome has about 23,000 genes. Half that of a rice plant, which has 46,000. How is this possible? Where are the genetic roots of our complexity? Here they are: abitane in the genome of an effective ally (when we respect it), the microbiota.
The term refers to all of the microorganisms who live there and have evolved with us for 200,000 years, since the beginning of the history of Homo sapiens, and Femina sapiens (!), refining their characteristics already present in primates, our ancestors, including monkeys and orangutans. The microbiota has a tremendous wealth of genes: approximately 3,300,000. These genes make up the microbiome, which allow it to perform countless biological functions, useful for its survival and for our survival. Longevity is the daughter of this provident alliance. According to some estimates, the human microbiota today is an invisible but powerful living body of about 39 trillion microorganisms. They outnumber the cells of an average human body, about 30 trillion. And then: which guest? Can we not respect, or worse, attack with the atomic bomb (antibiotics) a precious ally, with an army larger than ours? Except in cases where the ally turns against us, it is good to be very measured, wise and careful, before resorting to arms. Other strategies, such as careful use of prebiotics and probiotics, backed up by consistent healthy lifestyles, may prove more effective and successful in the long run.
Second thought: each of us has one unique and specific microbiota, strictly individual, such as a fingerprint or a face. The main strains that characterize it are the same throughout life, but their proportions change: the term dynamic holobiota designates this microbiological, ductile and resilient identity, which accompanies us throughout life. We are healthier and live longer the greater the biodiversity of the microbiota that coexists with us. How to protect it? The first care is the variety and quality of food. Excellent if it is sober, measured in calories, with fruits and vegetables, seeds, cereals and legumes, olive oil, fish and moderate amounts of eggs, meat or dairy products (except intolerances). Bad if he is monomaniac (I only eat pizza, or only yellow fruits and vegetables, as some teenagers say) with little food, and excess refined flours, yeasts, sugars, saturated fats and animal proteins. The second treatment is chrono-nutrition, that is to say the choice of the optimal time of day for different foods. The third is to be physically active because aerobic activity (walking!) optimizes metabolism, maintains the right body weight and avoids the accumulation of ectopic, displaced fat around the abdominal viscera. Having a belly, or worse, being obese, is a bad indicator of the longevity project: it reveals a dysfunctional microbiota (dysbiosis). It predicts diabetes, heart attacks, strokes and other pathologies that shorten health expectancy. Stress, alcohol and environmental toxins further weaken the microbiota, as does the loss of sex hormones in women after menopause.
The microbiota is also an endocrine gland: the term estrobolome refers to the genes of specialized microorganisms to process estrogen, produce it, or recirculate it for better use. After menopause, unless the woman is on hormone replacement therapy (HRT), estroboloma becomes minimal, visceral fat, belly fat and associated health risks increase. Conversely, the healthy microbiota is the guarantor of the health of the visceral and central brain, and of the intestine, which is the most important immunocompetent organ of the body. 80% of our defenses and the level of efficiency of our army, that is to say the immune system, is structured and trained in the intestine, thanks to the microbiota. Beyond lifestyle habits, and HRT when indicated, probiotics are the best allies for a healthy, varied and long-lasting microbiota. They are indicated at any age when external infections attack it, when it is ravaged with antibiotics, and in all situations of physical and/or mental stress. They are also an excellent anti-aging aid for men and women, in synergy with healthy lifestyles. For more information: www.olobiotico.it.
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